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3D Genetic code

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Picotechnology of Proteins

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Decoding  nucleotide sequences into  exact stereometric structures

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Hi-tech Kushelev Group




Get an exact stereometric model of the protein you are interested in

By specifying only the EMBL nucleotide sequence code or the mRNA for it

Approach



Dear Researchers!


Predicting the structure of a protein by nucleotide sequence, converting parametrization of biomolecules from internal coordinates (bond lengths, angles and torsions) to Cartesian coordinates is a fundamental task in molecular modeling.


We substantiated the possibility of constructing the exact spatial structures of proteins by their nucleotide sequences, based on the ring-polyhedral approach to atom modeling, which allowed us to detect the 3D genetic code.


To get your structure, send us the EMBL nucleotide sequence code of the protein of interest to you, or the mRNA for it.


Protein structures are provided in the form of the coordinate files of all nuclei and atoms, 2D and 3D diagrams, as well as in conventional form


Justification and confirmation of the method are given below. 




Toroidal (ring) models of particles as packets of standing waves Ring-polihedron models of  atoms
Peptide group included in the structure of all amino acid residues 3 D genetic code - algorithms for the rotation of amino acid residues relative to each other, according to  their  triplet letter codes

Stereometric structure

of DNA

Stereometric 

mechanism of translation



Accurate 2D Structures Accurate 3D, 4D and 5D Structures




Presentation

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Details

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RING ELECTRONS AND RING-POLYHEDRAL MODELS OF ATOMS


Picotechnology of Proteins' REVIEW


A.Yu.Kushelev 3D Genetic Code


The monograph  V.Sokolik, A.Kushelev  «Geometry of living nanoworld. Picotechnology of Proteins»


V Sokolik A Kushelev PIKOTECHNOLOGY - A NEW APPROACH TO MODELING THE SPATIAL STRUCTURE OF PROTEIN


The Essence of Picotecnology of Proteins


V.V.Sokolik    Isoacceptor tRNAs in the mechanism for the implementation of the 3D genetic code of proteins


V.V. Sokolik   Implementation of the 3D genetic code of proteins by isoacceptor tRNAs


V.V.Sokolik   THE MOLECULAR CONSTRUCTOR PROGRAM BUILDS STRUCTURAL TEMPLATES OF PROTEINS ACCORDING TO THEIR DETERMINING NUCLEOTIDE SEQUENCES


V V Sokolik   Protein is Coded in Genome and Sythesized in Ribosomes as a Structural Template of a Rotameric Version Sequence of Peptide Bond Configuration


V V Sokolik  MODELLING OF THE INDIVIDUAL STRUCTURAL TEMPLATE OF PROTEIN ON DETERMINING IT NUCLEOTIDE SEQUENCES


Picotechnology updates 2019


Picotechnology of Proteins - presentation by the author A.Kushelev


Human Genome Proteine 2D Picotechnology Structures Base 


Structural features in genomes


Algorithms for constructing 2D and 3D protein structures according to nucleotide sequence


V.Yakim, T.Riassina Picotechnology of proteins as an approach to modeling the spatial structure of the protein, complementing the possibilities of X-ray structural analysis


X-ray structural analysis and Picotechnology 2D diagrams. What do we see?


Picotechnology of translation


A.Yu. Kushelev, D.N. Kozhevnikov, V.V. Yakim, S.S. Markovskiy, V.V. Belyaev  CONSTRUCTION OF A SCALE-BASED MODEL OF A SPATIAL STRUCTURE OF A PROTEIN WITH ITS NUCLEOTIDE SEQUENCE


V.V. Sokolik Conundrum of Isoaceptort RNA


V.V. Sokolik "No additional information greater than that contained in DNA for protein folding is required"


How to see 3D structures on 2D Picotech diagram?


Examples of two highly ordered hypothetical proteins


Complex structures of 2D and 3D Picotech


Exotic helices of protein molecules


Sofware  helices and irregular structures in the protein molecule


Refinement of 2D structures of some G-proteins, taken from the NCBI database, using the Picotechnology method. Comparison


Terminating codons


V.Sokolik. ALGORITHM OF PROTEIN STRUCTURAL TEMPLATE DECODING ACCORDING TO ITS DETERMINED NUCLEOTIDE SEQUENCE


V. Sokolik. Modeling of the 3D structure of apoliprotezin E3 under its determining nucleotide sequence


V.V.Sokolik Predicting the in silico spatial structure of a protein based on genome information and a geometric algorithm as an alternative to the quantum mechanical approach


Picotechnological Anisotropic Pressure Reactors


The nuances of the functioning of the insulin hexamer picomachine


Thioalkalivibrio nitratireducens DSM 14787 protein


Software Protein Heliсes – are the Fractal Key to Genomes


Incredible molecules


Joint Pro and Proline tuning